OpenEvidence hits $15 billion valuation as AI reshapes how doctors treat patients

There’s a decent chance your doctor asked a chatbot about you this month. OpenEvidence, the AI search platform built for physicians, is now valued at $15 billion. The Miami-based startup reached that number in September 2026 after closing a $250 million funding round. Andreessen Horowitz and Byers Capital co-led the deal. For a company founded in 2022, that is a fast climb. A valuation that keeps getting revised upward The $15 billion mark is the latest step in a steep staircase. OpenEvidence was valued at $6 billion in October 2025. Earlier in 2026, that figure had already risen to $12 billion. Then came the September round, adding another $3 billion in a matter of months. The money has flowed in quickly too. OpenEvidence has pulled in over $1 billion in funding over 18 months. Backers include Sequoia, Thrive Capital, and Nvidia. Who is actually using it The usage numbers explain much of the investor enthusiasm. Nearly two-thirds of the roughly 1 million US physicians use OpenEvidence to help guide diagnoses and treatment decisions. Counting more broadly, over 1.12 million verified US clinicians were on the platform as of September 2026. The platform handled 42 million prompts in ...