The company says its AI did most of the work of porting Claude to AMD's MI355X chips, with minimal human help Moving a large AI model onto new hardware usually takes months of engineering. Anthropic says its AI handled most of that job itself. According to Anthropic, Claude Mythos enabled Claude to run on AMD’s MI355X GPUs in about three days, with minimal human help. What Anthropic says happened The work traces back to testing in July 2026. An Anthropic engineer reportedly connected Claude to the new AMD hardware and told it to get going. From there, the model handled the software migration and tuned performance across roughly three days. The research describes steadily improving performance curves, achieved without ongoing human intervention. AMD CEO Lisa Su reportedly confirmed that the assistance AMD offered turned out to be unnecessary. The hardware and the model The MI355X is built on AMD’s CDNA 4 architecture. It carries 288 GB of HBM3E memory and 8 TB/s of bandwidth, with up to 10 PFLOPS of peak performance. On November 9, 2026, Anthropic unveiled Claude Mythos 5.2, which it describes as its most advanced model yet in cybersecurity and life sciences. Mythos is not something...
Anthropic says Claude Mythos got Claude running on AMD GPUs in about three days
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